SCHEMBL308933

SCHEMBL308933

CCOC(=O)Oc1cccc(C)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
KMT2A Q03164 4/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 2/20 0.58
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.48
KLK7 P49862 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAPT P10636 4/20 0.48
ACHE P22303 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALOX5 P09917 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344222 0.91 KMT2A (0.51) LMNAKMT2AKDM4EMEN1CRHBP
SCHEMBL819332 0.87 LMNA (0.74) LMNAKMT2AMEN1GAASMN1; SMN2
SCHEMBL29418226 0.87 LMNA (0.74) LMNAKMT2AMEN1GAASMN1; SMN2
SCHEMBL6890528 0.86 LMNA (0.59) LMNAKMT2AKDM4EMEN1CRHBP
SCHEMBL14151440 0.85 KMT2A (0.64) LMNAKMT2AKDM4EMEN1CRHBP
SCHEMBL9410965 0.84 CYP3A4 (0.61) LMNAKMT2AKDM4EMEN1CRHBP
SCHEMBL6895062 0.84 ALDH1A1 (0.55) LMNAKMT2AL3MBTL1TDP1HPGD
SCHEMBL16675180 0.83 LMNA (0.69) LMNAKMT2AMEN1GAASMN1; SMN2
SCHEMBL13960012 0.83 KDM4E (0.47) LMNAKMT2AKDM4EMEN1CRHBP
SCHEMBL16359929 0.83 KMT2A (0.46) LMNAKMT2AKDM4EMEN1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421441-A1 CONCRETE COLORING COMPOSITIONS AND METHODS SWIMC LLC (US) 2019-01-02 EP disclosed
EP-2147075-B1 WEAK ACID BASED CONCRETE STAIN SWIMC LLC (US) 2018-12-05 EP disclosed
EP-2365946-B1 CONCRETE COLORING COMPOSITIONS AND METHODS VALSPAR SOURCING INC (US) 2018-07-04 EP disclosed
EP-2571090-B9 NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
US-9553333-B2 Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2017-01-24 US disclosed
US-9472828-B2 Nonaqueous electrolyte solution, electricity storage device using same, and trifluoromethylbenzene compound UBE INDUSTRIES, LTD. (JP) 2016-10-18 US disclosed
EP-2571090-B1 NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEM CORP (JP) 2016-09-07 EP disclosed
US-20150044554-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2015-02-12 US disclosed
CN-102209695-B Concrete coloring compositions and methods VALSPAR CORP 2014-12-24 CN disclosed
CN-101842457-B Weak acid based concrete stain VALSPAR CORP 2014-09-03 CN disclosed
WO-2008140694-A1 WEAK ACID BASED CONCRETE STAIN VALSPAR CORPORATION (US) 2008-11-20 WO disclosed
US-20080276387-A1 Weak Acid Based Concrete Stain SWIMC LLC 2008-11-13 US disclosed
WO-2008127714-A1 ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES PTC THERAPEUTICS, INC. (US) 2008-10-23 WO disclosed
US-20070281962-A2 Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration PCT THERAPEUTICS, INC. (US) 2007-12-06 US disclosed
US-6677331-B2 HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS MEIJI SEIKA KAISHA, LTD. (JP) 2004-01-13 US disclosed
US-20030149016-A1 Novel carbapenem derivatives KANO YUKO (JP) 2003-08-07 US disclosed
EP-1101766-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 2001-05-23 EP disclosed
EP-0760359-B1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL CO (JP) 1999-10-20 EP disclosed
US-5714627-A REACTING A DIALKYL CARBONATE WITH AN AROMATIC CARBOXYLIC ACID ARYL ESTER IN THE PRESENCE OF A CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-02-03 US disclosed
EP-0760359-A1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149016-A1 Novel carbapenem derivatives DPEP1, TMPRSS15, STK35 LMNA 2043/4885KMT2A 3040/4885KDM4E 1406/4885
US-20070281962-A2 Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration VEGFA, FLT4, MIF LMNA 3199/4885KMT2A 3947/4885KDM4E 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.