Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352288 | 1.00 | PLA2G1B (0.60) | PLA2G1BPOLBATG4BDNM1BCHE | |
| Hydrochloric Acid SCHEMBL5215664 | 0.86 | SIGMAR1 (0.48) | PLA2G1BPOLBATG4BSPPL2AF2 | |
| SCHEMBL6892334 | 0.85 | LMNA (0.61) | DNM1BCHELMNAF2PNMT | |
| SCHEMBL3350317 | 0.85 | LMNA (0.61) | DNM1BCHELMNAF2PNMT | |
| SCHEMBL3351836 | 0.85 | BCHE (0.53) | DNM1BCHELMNAOPRD1OPRK1 | |
| SCHEMBL6894816 | 0.85 | BCHE (0.53) | DNM1BCHELMNAOPRD1OPRK1 | |
| SCHEMBL3353939 | 0.84 | BCHE (0.61) | DNM1BCHELMNAF2OPRD1 | |
| SCHEMBL2605624 | 0.84 | BCHE (0.61) | DNM1BCHELMNAF2OPRD1 | |
| SCHEMBL496172 | 0.84 | BCHE (0.61) | DNM1BCHELMNAF2OPRD1 | |
| SCHEMBL7951036 | 0.84 | BCHE (0.61) | DNM1BCHELMNAF2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |