Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1115855 | 0.78 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL818042 | 0.76 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL9225199 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2865755 | 0.64 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL27513924 | 0.64 | GPR3 (0.35) | GPR3 | |
| SCHEMBL8853881 | 0.63 | SLC6A4 (0.41) | GPR3 | |
| Hydrochloric Acid SCHEMBL647071 | 0.62 | GPR3 (0.35) | GPR3 | |
| Hydrochloric Acid SCHEMBL7185531 | 0.62 | GPR3 (0.34) | GPR3 | |
| SCHEMBL6813661 | 0.62 | GPR3 (0.34) | GPR3 | |
| Hydrochloric Acid SCHEMBL3661444 | 0.61 | GPR3 (0.33) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713426-B1 | METHYL(PHENYL)METHYLENE)(9-FLUORENYL)(CYCLOPENTADIENYL) ZIRCONIUM DICHLORIDE OR THE (DIPHENYLMETHYLENE) COMPLEX; VERY HIGH MOLECULAR WEIGHT, NARROW MOLECULAR WEIGHT DISTRIBUTION; MOLDINGS ARE TRANSPARENT, FLEXIBLE, TEAR RESISTANT, AND GLOSSY | BASELL POLYOLEFINE GMBH (DE) | 2004-03-30 | — | — | US | disclosed |