Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201860 | 0.84 | CA1 (0.61) | SMN1; SMN2ALDH1A1MAPTHTTPARP10 | |
| SCHEMBL11119945 | 0.83 | NR4A2 (0.64) | NPC1RAB9AALDH1A1MAPTMAOB | |
| SCHEMBL12339549 | 0.83 | PARP10 (0.83) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6890765 | 0.83 | PARP10 (0.70) | NPC1RAB9ASMN1; SMN2MAPTMAOB | |
| SCHEMBL20000873 | 0.82 | APP (0.80) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13424151 | 0.78 | APP (0.69) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28335896 | 0.78 | RAB9A (1.00) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL933577 | 0.78 | MAOB (0.76) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1186510 | 0.78 | RAB9A (1.00) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13238323 | 0.78 | SMN1; SMN2 (0.69) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5698692-A | INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |