Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | VKORC1 | Q9BQB6 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | PCSK7 | Q16549 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514111 | 0.80 | ALDH1A1 (0.51) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL3778823 | 0.80 | ALDH1A1 (0.51) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL7351830 | 0.79 | ALDH1A1 (0.50) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL6890789 | 0.76 | CYP2C9 (0.52) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL2358729 | 0.74 | LMNA (0.48) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL7354341 | 0.73 | KDM4E (0.55) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL9286035 | 0.72 | NQO1 (0.53) | ALDH1A1VKORC1CYP2C9KDM4EPCSK7 | |
| SCHEMBL1649890 | 0.72 | NQO1 (0.50) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL5103338 | 0.71 | NQO1 (0.52) | ALDH1A1VKORC1CYP2C9KDM4EALB | |
| SCHEMBL12091846 | 0.70 | CA12 (0.49) | ALDH1A1VKORC1CYP2C9KDM4EALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278436-B2 | Glycosylated warfarin analogs and uses thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100267655-A1 | Glycosylated Warfarin Analogs and Uses Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-10-21 | — | — | US | disclosed |
| WO-2010014814-A2 | GLYCOSYLATED WARFARIN ANALOGS AND USES THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267655-A1 | Glycosylated Warfarin Analogs and Uses Thereof | GPI, UGGT1, GALE | ALDH1A1 1073/4885VKORC1 8/4885CYP2C9 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.