Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895656 | 0.87 | MEN1 (0.64) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6894927 | 0.84 | ANPEP (0.40) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6895745 | 0.81 | LMNA (0.47) | LMNAMEN1KMT2ACASRCYP1A2 | |
| SCHEMBL6894820 | 0.81 | CYP1A2 (0.60) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6890574 | 0.80 | PLA2G1B (0.52) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3649450 | 0.80 | TACR1 (0.46) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6896828 | 0.78 | LMNA (0.48) | LMNAKMT2ACASRALDH1A1 | |
| SCHEMBL6892337 | 0.77 | LMNA (0.52) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6892177 | 0.77 | ATM (0.42) | CASRCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7637536 | 0.77 | MEN1 (0.72) | LMNAMEN1KMT2ACASRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |