Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890978 | 0.84 | LMNA (0.50) | ALDH1A1KDM4ELMNAADRA2AADRA2C | |
| SCHEMBL6895745 | 0.82 | LMNA (0.47) | ALDH1A1KDM4ELMNAADRA2AADRA2C | |
| SCHEMBL6892177 | 0.78 | ATM (0.42) | ATML3MBTL1CYP2D6POLB | |
| SCHEMBL6895656 | 0.78 | MEN1 (0.64) | ALDH1A1ATML3MBTL1MEN1CYP1A2 | |
| SCHEMBL6895263 | 0.77 | KDM4E (0.43) | ANPEPALDH1A1KDM4ELMNAADRA2A | |
| SCHEMBL6894924 | 0.77 | KDM4E (0.43) | ANPEPALDH1A1KDM4ELMNAADRA2A | |
| SCHEMBL6895808 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1KDM4ELMNAMEN1CYP1A2 | |
| SCHEMBL6894820 | 0.76 | CYP1A2 (0.60) | ALDH1A1KDM4ELMNAATML3MBTL1 | |
| SCHEMBL6887798 | 0.76 | GAA (0.45) | ALDH1A1KDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL6895074 | 0.75 | HPGD (0.44) | ANPEPALDH1A1KDM4ELMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |