Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890978 | 0.87 | LMNA (0.50) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6894820 | 0.82 | CYP1A2 (0.60) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6892337 | 0.81 | LMNA (0.52) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3649450 | 0.81 | TACR1 (0.46) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6890574 | 0.79 | PLA2G1B (0.52) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23754498 | 0.78 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23754506 | 0.78 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29864910 | 0.78 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6894927 | 0.78 | ANPEP (0.40) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6895745 | 0.77 | LMNA (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |