Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891578 | 1.00 | ADORA3 (0.62) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL10752470 | 1.00 | ADORA3 (0.62) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL10755250 | 0.94 | ALDH1A1 (0.64) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL10755255 | 0.94 | ALDH1A1 (0.64) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL17719415 | 0.88 | ADORA3 (0.56) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL25518100 | 0.87 | ADORA3 (0.66) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL6889075 | 0.86 | ALDH1A1 (0.65) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL6889074 | 0.86 | ALDH1A1 (0.65) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL13084156 | 0.81 | ALDH1A1 (0.81) | ADORA3NR1I2PTGS2PGRPDE4D | |
| SCHEMBL1496221 | 0.81 | ALDH1A1 (0.68) | ADORA3NR1I2PTGS2PGRPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823895-B1 | FATTY ACID ESTERS AS BIOACTIVE COMPOUNDS | SCARISTA LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-6245811-B1 | DIFFUSION THROUGH CELL BARRIERS | SCOTIA HOLDINGS PLC (GB) | 2001-06-12 | — | — | US | disclosed |