Sugi Predict

Sugi Predict / Compounds / SCHEMBL25518100

SCHEMBL25518100

SCHEMBL25518100

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(C)C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 2/20 0.66
▸ NR1I2 O75469 2/20 0.66
▸ PTGS2 P35354 2/20 0.66
▸ PGR P06401 1/20 0.66
▸ PDE4D Q08499 1/20 0.66
▸ ALDH1A1 P00352 6/20 0.59
▸ F7 P08709 3/20 0.59
▸ CYP19A1 P11511 3/20 0.59
▸ F3 P13726 3/20 0.59
▸ PTGS1 P23219 2/20 0.59
▸ PPARG P37231 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ PPARD Q03181 2/20 0.59
▸ PPARA Q07869 2/20 0.59
▸ OXER1 Q8TDS5 2/20 0.59
▸ RXRA P19793 1/20 0.59
▸ CYP3A4 P08684 2/20 0.58
▸ ALOX15 P16050 2/20 0.58
▸ HSD17B10 Q99714 2/20 0.58
▸ TDP1 Q9NUW8 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1496221 0.94 ALDH1A1 (0.68) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL11232433 0.90 LMNA (0.66) NR1I2PTGS2ALDH1A1F7CYP19A1
SCHEMBL3662637 0.89 CNR1 (0.73) ALDH1A1CYP19A1PPARGKMT2APPARD
SCHEMBL3662634 0.89 CNR1 (0.73) ALDH1A1CYP19A1PPARGKMT2APPARD
SCHEMBL23754250 0.88 LMNA (0.62) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL12615033 0.88 LMNA (0.62) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL6891573 0.87 ADORA3 (0.62) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL6891578 0.87 ADORA3 (0.62) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL10752470 0.87 ADORA3 (0.62) ADORA3NR1I2PTGS2PGRPDE4D
SCHEMBL2354771 0.87 ALDH1A1 (0.81) ADORA3NR1I2PTGS2PGRPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 — — US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 — — US disclosed
US-20230132808-A1 WNT/CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CITY OF HOPE 2023-05-04 — — US disclosed
US-20230132808-A1 WNT/CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CITY OF HOPE 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 ADORA3 3236/4885NR1I2 794/4885PTGS2 1423/4885
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, EP300 ADORA3 3236/4885NR1I2 794/4885PTGS2 1423/4885
US-20230132808-A1 WNT/CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF WNT1, WNT3A, CREBBP ADORA3 4318/4885NR1I2 1152/4885PTGS2 3027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.