Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 1/20 | 0.65 |
| ▸ | F7 | P08709 | 4/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889074 | 1.00 | ALDH1A1 (0.65) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL17008819 | 0.94 | PRKCA (0.59) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL17008822 | 0.94 | PRKCA (0.59) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL10755255 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL10755250 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL29093680 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL8706806 | 0.88 | LMNA (0.69) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL10752470 | 0.86 | ADORA3 (0.62) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL6891578 | 0.86 | ADORA3 (0.62) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL6891573 | 0.86 | ADORA3 (0.62) | ALDH1A1HPGDFAAHMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823895-B1 | FATTY ACID ESTERS AS BIOACTIVE COMPOUNDS | SCARISTA LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| EP-0823897-B1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCARISTA LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-6245811-B1 | DIFFUSION THROUGH CELL BARRIERS | SCOTIA HOLDINGS PLC (GB) | 2001-06-12 | — | — | US | disclosed |
| EP-0823895-A1 | FATTY ACID ESTERS AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034855-A1 | FATTY ACID ESTERS AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |