Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124242 | 0.90 | TP53 (0.52) | LMNAEPHX1TP53TSHR | |
| SCHEMBL14839517 | 0.84 | RIPK1 (0.50) | MAPTRAB9ALMNARIPK1NPC1 | |
| SCHEMBL30849677 | 0.84 | RIPK1 (0.50) | MAPTRAB9ALMNARIPK1NPC1 | |
| SCHEMBL29153353 | 0.82 | TP53 (0.45) | MAPTRAB9ALMNANPC1MEN1 | |
| SCHEMBL28896863 | 0.82 | MEN1 (0.49) | RAB9ALMNANPC1MEN1CYP1A2 | |
| SCHEMBL11396984 | 0.81 | ESR1 (0.48) | MAPTALDH1A1RAB9ALMNARIPK1 | |
| SCHEMBL125923 | 0.80 | LMNA (0.58) | LMNARIPK1CYP1A2SLC6A2SLC6A4 | |
| SCHEMBL4355212 | 0.80 | LMNA (0.58) | LMNARIPK1CYP1A2SLC6A2SLC6A4 | |
| SCHEMBL13232184 | 0.79 | TRPA1 (0.50) | MAPTRAB9ALMNANPC1MEN1 | |
| SCHEMBL10021101 | 0.79 | CNR1 (0.49) | LMNACYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213293-B1 | Use of chiral, uncharged metal compounds as doting agents for liquid crystals | BASF AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1213293-A1 | Use of chiral, uncharged metal compounds as doting agents for liquid crystals | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-12 | — | — | EP | disclosed |