Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892400 | 0.92 | SRD5A2 (0.59) | SRD5A2PTPN11RARBHCRTR1HCRTR2 | |
| SCHEMBL2997357 | 0.84 | SMN1; SMN2 (0.56) | SRD5A2PTPN11RXRASMN1; SMN2TP53 | |
| SCHEMBL9652658 | 0.83 | SRD5A2 (0.57) | SRD5A2PTPN11RARBRXRARXRB | |
| SCHEMBL6884735 | 0.79 | RXRA (0.51) | SRD5A2PTPN11RARBHSD17B10RXRA | |
| SCHEMBL2635961 | 0.79 | BCL2 (0.50) | SRD5A2RARBHCRTR1HCRTR2RXRA | |
| SCHEMBL6891189 | 0.78 | HSD17B10 (0.59) | SRD5A2RARBHSD17B10RXRARXRB | |
| SCHEMBL2997363 | 0.78 | SRD5A2 (0.63) | SRD5A2PTPN11HCRTR1HCRTR2HSD17B10 | |
| SCHEMBL9751648 | 0.78 | BCL2 (0.58) | SRD5A2RARBHCRTR1HCRTR2RXRA | |
| SCHEMBL322440 | 0.77 | CA1 (0.59) | SRD5A2PPARGPPARAHSD17B10RXRA | |
| SCHEMBL717095 | 0.77 | ALDH1A1 (0.54) | SRD5A2RXRARXRBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003561-A9 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | UNIV NORTHWESTERN (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004003561-A1 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | NORTHWESTERN UNIVERSITY (US) | 2004-01-08 | — | — | WO | disclosed |