Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 5/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892386 | 0.92 | SRD5A2 (0.53) | SRD5A2PTPN11HCRTR1HCRTR2HSD17B10 | |
| SCHEMBL2997363 | 0.84 | SRD5A2 (0.63) | SRD5A2PTPN11HCRTR1HCRTR2HSD17B10 | |
| SCHEMBL9652658 | 0.80 | SRD5A2 (0.57) | SRD5A2PTPN11RXRARXRBRARB | |
| SCHEMBL6891189 | 0.78 | HSD17B10 (0.59) | SRD5A2HSD17B10RXRARXRBRARB | |
| SCHEMBL2997357 | 0.78 | SMN1; SMN2 (0.56) | SRD5A2PTPN11RXRACYP2C8CA1 | |
| SCHEMBL8437505 | 0.77 | NR4A2 (0.62) | SRD5A2HCRTR1HCRTR2RXRARXRB | |
| SCHEMBL25126172 | 0.77 | RXRA (0.59) | SRD5A2HSD17B10RXRARXRBRARB | |
| SCHEMBL322440 | 0.77 | CA1 (0.59) | SRD5A2HSD17B10RXRARXRBCA1 | |
| SCHEMBL6884342 | 0.76 | SRD5A2 (0.53) | SRD5A2PTPN11HSD17B10RXRARXRB | |
| SCHEMBL9751648 | 0.75 | BCL2 (0.58) | SRD5A2HCRTR1HCRTR2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003561-A9 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | UNIV NORTHWESTERN (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004003561-A1 | PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME | NORTHWESTERN UNIVERSITY (US) | 2004-01-08 | — | — | WO | disclosed |