Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894145 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL7926967 | 0.72 | EGLN1 (0.35) | EGLN1 | |
| SCHEMBL12187907 | 0.71 | CTSK (0.33) | — | |
| SCHEMBL16447016 | 0.71 | EGLN1 (0.38) | EGLN1MEN1KMT2A | |
| SCHEMBL10041806 | 0.68 | LMNA (0.45) | EGLN1 | |
| SCHEMBL8868949 | 0.68 | EGLN1 (0.38) | EGLN1 | |
| SCHEMBL29172779 | 0.66 | KMT2A (0.41) | KMT2A | |
| SCHEMBL578668 | 0.66 | LMNA (0.68) | EGLN1 | |
| SCHEMBL11314635 | 0.65 | EGLN1 (0.49) | EGLN1MEN1KMT2A | |
| SCHEMBL1912605 | 0.65 | EGLN1 (0.63) | EGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025849-A1 | PROCESSES FOR PREPARING PROTEASE INHIBITORS OF HEPATITIS C VIRUS | MERCK SHARP & DOHME CORP. (US) | 2011-03-03 | — | — | WO | disclosed |