SCHEMBL16447016

SCHEMBL16447016

C#CCOC(=O)NCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 3/20 0.38
TSHR P16473 2/20 0.38
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 3/20 0.36
TAAR1 Q96RJ0 1/20 0.36
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PTGS2 P35354 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22508748 0.81 ALDH1A1 (0.42) TSHRNPC1ALDH1A1TAAR1L3MBTL1
SCHEMBL16106831 0.80 TSHR (0.44) TSHRNPC1ALDH1A1TAAR1POLB
SCHEMBL19672964 0.79 EGLN1 (0.38) EGLN1ALDH1A1ZDHHC20SLC1A3SLC1A2
SCHEMBL16401454 0.78 NPC1 (0.39) TSHRNPC1ALDH1A1TAAR1POLB
SCHEMBL15549900 0.77 HTT (0.51) TSHRALDH1A1TAAR1L3MBTL1ZDHHC20
SCHEMBL1264448 0.77
SCHEMBL10245233 0.77
SCHEMBL9353138 0.76 EGLN1 (0.36) EGLN1ALDH1A1LMNAMAPTPTGS2
SCHEMBL22508885 0.76 TSHR (0.49) TSHRL3MBTL1ZDHHC20CYP1A2CYP2D6
SCHEMBL15806526 0.75 L3MBTL1 (0.51) L3MBTL1ZDHHC20TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US disclosed
WO-2025111431-A1 ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF LES LABORATOIRES SERVIER (FR) 2025-05-30 WO disclosed
EP-4525927-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF Novartis AG (CH) 2025-03-26 EP disclosed
EP-4525928-A1 ANTIBODY DRUG CONJUGATES Novartis AG (CH) 2025-03-26 EP disclosed
CN-119613486-A Antibody drug conjugates with linkers comprising hydrophilic groups 诺华股份有限公司 2025-03-14 CN disclosed
CN-119613487-A Antibody drug conjugates with linkers comprising hydrophilic groups 诺华股份有限公司 2025-03-14 CN disclosed
CN-113853219-B Antibody drug conjugates with linkers comprising hydrophilic groups 诺华股份有限公司 2025-01-07 CN disclosed
WO-2023223097-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2023-11-23 WO disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 WO disclosed
EP-3972650-A2 ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS Novartis AG (CH) 2022-03-30 EP disclosed
CN-113853219-A Antibody drug conjugates with linkers comprising hydrophilic groups 诺华股份有限公司 2021-12-28 CN disclosed
US-20210284668-A1 GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIBIOTIC PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-09-16 US disclosed
WO-2020236841-A2 ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS NOVARTIS AG (CH) 2020-11-26 WO disclosed
EP-3030545-B1 AMINO ACID DERIVATIVES MEDIMMUNE LTD (GB) 2020-10-07 EP disclosed
WO-2019243273-A1 GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIOBIOTIC PROPERTIES UNIVERSITÉ DE STRASBOURG (FR) 2019-12-26 WO disclosed
US-9981908-B2 Amino acid derivatives MEDIMMUNE LIMITED (GB) 2018-05-29 US disclosed
US-20160176811-A1 Amino Acid Derivatives ALLOZYNE, INC. 2016-06-23 US disclosed
EP-3030545-A2 AMINO ACID DERIVATIVES Medimmune Limited (GB) 2016-06-15 EP disclosed
WO-2015019192-A2 AMINO ACID DERIVATIVES MEDIMMUNE LIMITED (GB) 2015-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284668-A1 GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIBIOTIC PROPERTIES PADI3, PADI1, PADI4 EGLN1 3245/4885TSHR 779/4885NPC1 2753/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 EGLN1 3340/4885TSHR 3232/4885NPC1 2842/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 EGLN1 2547/4885TSHR 1235/4885NPC1 814/4885
US-20160176811-A1 Amino Acid Derivatives BCAT2, BCAT1, DAO EGLN1 2399/4885TSHR 540/4885NPC1 4789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.