Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165514 | 0.87 | MEN1 (0.47) | MEN1KMT2ACASR | |
| SCHEMBL6886251 | 0.85 | TDP1 (0.52) | SMN1; SMN2MEN1MAPK1KMT2ANPSR1 | |
| SCHEMBL6895924 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2MEN1MAPK1KMT2ANPSR1 | |
| SCHEMBL6895745 | 0.83 | LMNA (0.47) | SMN1; SMN2MEN1MAPK1KMT2ANPSR1 | |
| SCHEMBL6892177 | 0.81 | ATM (0.42) | POLBCASRL3MBTL1CYP2D6EPHX2 | |
| SCHEMBL6895808 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1MAPK1KMT2ANPSR1 | |
| SCHEMBL6894820 | 0.80 | CYP1A2 (0.60) | SMN1; SMN2MEN1MAPK1KMT2ANPSR1 | |
| SCHEMBL6887059 | 0.78 | TACR1 (0.50) | — | |
| SCHEMBL6887798 | 0.77 | GAA (0.45) | MAPTSMN1; SMN2MAPK1NPSR1ALDH1A1 | |
| SCHEMBL164926 | 0.76 | HTR2A (0.50) | EPHX1MAPTLMNAOPRM1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |