SCHEMBL6892670

SCHEMBL6892670

CCCCCCCCCCCCCCCCC(NC)C(C)NC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.41
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
SPHK1 Q9NYA1 1/20 0.39
LMNA P02545 1/20 0.38
DNM1 Q05193 2/20 0.37
EPHX1 P07099 1/20 0.37
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36
ACE2 Q9BYF1 1/20 0.35
ALDH1A1 P00352 1/20 0.35
FDPS P14324 3/20 0.34
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895295 1.00 OPRM1 (0.41) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL19824689 0.91 DNM1 (0.35) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL21143019 0.84 DNM1 (0.41) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL11299774 0.84 OPRM1 (0.42) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL19200976 0.83 ADH1B (0.38) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL24394272 0.81 OPRM1 (0.44) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL24409398 0.81 OPRM1 (0.44) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL20322479 0.81 OPRM1 (0.37) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL19647379 0.80 ADH1B (0.39) OPRM1ADH1BADH1CADH1AADH4
SCHEMBL6895292 0.80 SPHK1 (0.52) OPRM1ADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0886551-B1 STABILITY CONTROL AGENT COMPOSITION FOR POLYOLEFIN FOAM KNAUS DENNIS A (US) 2004-08-04 EP claimed
EP-0886551-B1 STABILITY CONTROL AGENT COMPOSITION FOR POLYOLEFIN FOAM KNAUS DENNIS A (US) 2004-08-04 EP disclosed
US-5874024-A A STABILIZER FOR INHIBITING POLYMER SHRINKAGE COMPRISING AT LEAST ONE COMPOUND THAT IS A PARTIAL ESTER OF A FATTY ACID WITH POLYOL AND AT LEAST ONE COMPOUND SELECTED FROM HIGHER ALKYL AMINES OR FATTY ACID AMIDES KNAUS DENNIS A (US) 1999-02-23 US disclosed
US-5750584-A CONSISTING OF ESTER OF FATTY ACID WITH POLYOLS,HIGHER ALKYL AMINES AND FATTY AMIDES KNAUS DENNIS A (US) 1998-05-12 US disclosed
US-RE31744-E Expanded olefin polymer ASAHI-DOW LIMITED (JP) 1984-11-20 US disclosed
EP-0001791-B1 EXPANDABLE OLEFIN POLYMER COMPOSITION, EXPANDED PRODUCTS MADE THEREFROM AND METHOD OF MAKING THE EXPANDED PRODUCTS THE DOW CHEMICAL COMPANY (US) 1983-09-28 EP disclosed
US-4343913-A AMIDE OR ESTER ADDITIVE TO PREVENT SHRINKAGE ASAHI-DOW LIMITED (JP) 1982-08-10 US disclosed
US-4214054-A Expanded olefin polymer ASAHI-DOW LIMITED (JP) 1980-07-22 US disclosed
EP-0001791-A2 Expandable olefin polymer composition, expanded products made therefrom and method of making the expanded products THE DOW CHEMICAL COMPANY (US) 1979-05-16 EP disclosed