SCHEMBL21143019

SCHEMBL21143019

CCCCCCC(NC)C(C)CCCC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.41
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
OPRM1 P35372 1/20 0.39
SPHK1 Q9NYA1 1/20 0.38
LMNA P02545 1/20 0.37
S1PR2 O95136 5/20 0.36
S1PR1 P21453 5/20 0.36
S1PR3 Q99500 5/20 0.36
S1PR4 O95977 4/20 0.36
EPHX1 P07099 1/20 0.36
CA2 P00918 1/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
SMPD1 P17405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19708736 0.89 OPRM1 (0.41) DNM1ADH1BADH1CADH1AADH4
SCHEMBL19647379 0.87 ADH1B (0.39) DNM1ADH1BADH1CADH1AADH4
SCHEMBL21158918 0.86 ALDH1A1 (0.33) DNM1OPRM1TSHR
SCHEMBL14885134 0.86 ALDH1A1 (0.33) DNM1OPRM1TSHR
SCHEMBL19200976 0.85 ADH1B (0.38) DNM1ADH1BADH1CADH1AADH4
SCHEMBL6895295 0.84 OPRM1 (0.41) DNM1ADH1BADH1CADH1AADH4
SCHEMBL6892670 0.84 OPRM1 (0.41) DNM1ADH1BADH1CADH1AADH4
SCHEMBL24685859 0.82 ALDH1A1 (0.38) DNM1OPRM1CA2TSHR
SCHEMBL22296073 0.82 ALDH1A1 (0.38) DNM1OPRM1CA2TSHR
SCHEMBL11299774 0.82 OPRM1 (0.42) DNM1ADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10961180-B2 Branched trialkyl amine oxides EASTMAN CHEMICAL COMPANY (US) 2021-03-30 US disclosed
US-10640452-B2 Branched trialkyl quaternary ammonium compounds EASTMAN CHEMICAL COMPANY (US) 2020-05-05 US disclosed
US-20190218169-A1 BRANCHED TRIALKYL AMINE OXIDES EASTMAN CHEMICAL COMPANY (US) 2019-07-18 US disclosed
US-20190218170-A1 BRANCHED TRIALKYLAMINE PRECURSORS, INTERMEDIATES, PRODUCTS MADE THEREFROM AND PROCESSES OF MANUFACTURE EASTMAN CHEMICAL COMPANY (US) 2019-07-18 US disclosed
US-20190218171-A1 BRANCHED TRIALKYL QUATERNARY AMMONIUM COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218169-A1 BRANCHED TRIALKYL AMINE OXIDES C5, OR10J3, ALKBH5 DNM1 4865/4885ADH1B 1427/4885ADH1C 133/4885
US-20190218171-A1 BRANCHED TRIALKYL QUATERNARY AMMONIUM COMPOUNDS ELOVL3, ELOVL5, ALK DNM1 1704/4885ADH1B 3775/4885ADH1C 231/4885
US-10640452-B2 Branched trialkyl quaternary ammonium compounds BCKDK, PFKL, GLUL DNM1 2807/4885ADH1B 4331/4885ADH1C 3435/4885
US-20190218170-A1 BRANCHED TRIALKYLAMINE PRECURSORS, INTERMEDIATES, PRODUCTS MADE THEREFROM AND PROCESSES OF MANUFACTURE ACADM, ALK, FASN DNM1 4242/4885ADH1B 1891/4885ADH1C 85/4885
US-10961180-B2 Branched trialkyl amine oxides C5, OR10J3, ALKBH5 DNM1 4865/4885ADH1B 1427/4885ADH1C 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.