SCHEMBL689339

SCHEMBL689339

Oc1cccc2nn[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 3/20 0.35
EGFR P00533 3/20 0.35
CA2 P00918 2/20 0.35
LMNA P02545 2/20 0.35
FYN P06241 2/20 0.35
MMP9 P14780 2/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
RECQL P46063 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ADAMTS4 O75173 1/20 0.35
CA1 P00915 1/20 0.35
MMP2 P08253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4573586 0.98 ACHE (0.40) ACHEALDH1A1MAPTRAB9AGAA
SCHEMBL3081638 0.77 MEN1 (0.32) ALDH1A1GAAKMT2AL3MBTL1
SCHEMBL9207975 0.74
SCHEMBL863550 0.74
SCHEMBL3085049 0.74 AXL (0.41) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL24388617 0.74 NOS1 (0.35)
SCHEMBL204654 0.74 NOS1 (0.44) GAAPSMB8CA12CYP1A2AR
SCHEMBL4217491 0.74 GAA (0.37) ALDH1A1MAPTRAB9AGAANPSR1
SCHEMBL16178984 0.74 PARP1 (0.35) ALDH1A1MAPTRAB9AGAATDP1
SCHEMBL29491115 0.74 ENPP2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108641579-A Environment-friendly aqueous paint of one kind and preparation method thereof 浙江夏远信息技术有限公司 2018-10-12 CN claimed
CN-119119189-A Polypeptides having MMP2 inhibitory effect 大正制药株式会社 2024-12-13 CN disclosed
US-11124609-B2 Polymeric coatings for metal surfaces SEABOURNE SOLUTIONS, LLC (US) 2021-09-21 US disclosed
US-20190211154-A1 POLYMERIC COATINGS FOR METAL SURFACES SEABOURNE SOLUTIONS (US) 2019-07-11 US disclosed
CN-108641579-A Environment-friendly aqueous paint of one kind and preparation method thereof 浙江夏远信息技术有限公司 2018-10-12 CN disclosed
EP-3083587-B1 OXIMINO DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA CADILA HEALTHCARE LTD (IN) 2018-04-04 EP disclosed
WO-2018026648-A1 POLYMERIC COATINGS FOR METAL SURFACES SEABOURNE SOLUTIONS (US) 2018-02-08 WO disclosed
US-9827257-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2017-11-28 US disclosed
US-9750759-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2017-09-05 US disclosed
EP-2597091-B1 Antitumoral Compounds PHARMA MAR SA (ES) 2016-04-20 EP disclosed
CN-1675180-A Indole, indazole, and benzazole derivative SUMITOMO PHARMA (JP) 2005-09-28 CN disclosed
EP-1157827-B1 Computer-to-plate by ink jet AGFA GEVAERT (BE) 2005-08-17 EP disclosed
EP-1514869-A1 INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-03-16 EP disclosed
US-6457413-B1 Computer-to-plate by ink jet AGFA-GEVAERT (BE) 2002-10-01 US disclosed
US-6457413-B1 Computer-to-plate by ink jet AGFA-GEVAERT (BE) 2002-10-01 US disclosed
US-20020043171-A1 Computer-to-plate by ink jet AGFA GRAPHICS NV (BE) 2002-04-18 US disclosed
US-20020043171-A1 Computer-to-plate by ink jet AGFA GRAPHICS NV (BE) 2002-04-18 US disclosed
EP-1157827-A1 Computer-to-plate by ink jet AGFA-GEVAERT N.V. (BE) 2001-11-28 EP disclosed
EP-1157827-A1 Computer-to-plate by ink jet AGFA-GEVAERT N.V. (BE) 2001-11-28 EP disclosed
US-4415629-A Insulated conductor ELECTRIC POWER RESEARCH INSTITUTE, INC. (US) 1983-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124609-B2 Polymeric coatings for metal surfaces PUF60, VMP1, VAPA ACHE 1299/4885ALDH1A1 3294/4885MAPT 772/4885
US-20190211154-A1 POLYMERIC COATINGS FOR METAL SURFACES PUF60, VMP1, VAPA ACHE 1299/4885ALDH1A1 3294/4885MAPT 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.