Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207975 | 0.74 | — | — | |
| SCHEMBL3085049 | 0.74 | AXL (0.41) | CHEK1FLT3PLK3PARP1GAA | |
| SCHEMBL863550 | 0.74 | — | — | |
| SCHEMBL689339 | 0.74 | ACHE (0.41) | ARPSMB8CA12CYP1A2GAA | |
| SCHEMBL4217491 | 0.74 | GAA (0.37) | CHEK1AHRARPARP1CA9 | |
| SCHEMBL24388617 | 0.74 | NOS1 (0.35) | NOS1CLK1DYRK1ACLK4DYRK1B | |
| SCHEMBL16178984 | 0.74 | PARP1 (0.35) | DAOPARP1CA12CA9GAA | |
| SCHEMBL21120441 | 0.73 | — | — | |
| Water SCHEMBL4573586 | 0.72 | ACHE (0.40) | ARPSMB8CA12CYP1A2GAA | |
| SCHEMBL30958241 | 0.72 | KEAP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4660199-A1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | Sage Therapeutics, Inc. (US) | 2025-12-10 | — | — | EP | disclosed |
| EP-3719030-B1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | SAGE THERAPEUTICS INC (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-3719030-B1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | SAGE THERAPEUTICS INC (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-117304245-A | 19-nor steroids that stimulate neural activity and methods of use thereof | 萨奇治疗股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-112110976-B | 19-nor steroids that stimulate neural activity and methods of use thereof | 萨奇治疗股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11261211-B2 | 19-NOR neuroactive steroids and methods of use thereof | SAGE THERAPEUTICS, INC. (US) | 2022-03-01 | — | — | US | disclosed |
| CN-112110976-A | 19-nor steroids that stimulate neural activity and methods of use thereof | 萨奇治疗股份有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-105246909-B | 19-nor steroids that stimulate neural activity and methods of use thereof | 萨奇治疗股份有限公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-3719030-A1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | Sage Therapeutics, Inc. (US) | 2020-10-07 | — | — | EP | disclosed |
| EP-3719030-A1 | 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION | Sage Therapeutics, Inc. (US) | 2020-10-07 | — | — | EP | disclosed |
| US-20120149750-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2012-06-14 | — | — | US | disclosed |
| US-8088801-B2 | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2012-01-03 | — | — | US | disclosed |
| CN-102272105-A | enantiomerically enriched aryloazol-2-yl cyanoethylamino parasiticidal compounds | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2364301-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL- 2 -YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS | Merial Limited (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010056999-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL- 2 -YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS | MERIAL LIMITED (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100125089-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2010-05-20 | — | — | US | disclosed |
| EP-2155699-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | Merial Limited (US) | 2010-02-24 | — | — | EP | disclosed |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL, INC. | 2008-12-18 | — | — | US | disclosed |
| WO-2008144275-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2008-11-27 | — | — | WO | disclosed |
| US-4585472-A | PRE- AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149750-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | NOS1 2909/4885CHEK1 3485/4885FLT3 349/4885 |
| US-20080312272-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4X1, CBR3, TYR | NOS1 2909/4885CHEK1 3485/4885FLT3 349/4885 |
| US-20100125089-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | CYP4B1, NPY4R, CYP4X1 | NOS1 3939/4885CHEK1 3738/4885FLT3 542/4885 |
| US-11261211-B2 | 19-NOR neuroactive steroids and methods of use thereof | NR3C2, HSD3B1, NR3C1 | NOS1 323/4885CHEK1 4402/4885FLT3 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.