Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661772 | 0.75 | NAAA (0.56) | — | |
| SCHEMBL18654084 | 0.75 | NAAA (0.56) | — | |
| SCHEMBL14303692 | 0.70 | HPGD (0.61) | LMNAMEN1KMT2ANPC1CACNA1H | |
| SCHEMBL904476 | 0.67 | GABBR2 (0.55) | LMNABCAT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9061130 | 0.67 | LMNA (0.54) | LMNABCAT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20658834 | 0.67 | — | — | |
| SCHEMBL904490 | 0.67 | GABBR2 (0.55) | LMNABCAT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL186610 | 0.67 | GABBR2 (0.55) | LMNABCAT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18390245 | 0.67 | GAA (0.58) | CACNA1HCACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL1373206 | 0.66 | GABBR2 (0.53) | LMNABCAT2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | disclosed |