Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 5/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493890 | 0.78 | PLA2G1B (0.50) | PLA2G1BATG4BLOXL2IDO1TAAR1 | |
| SCHEMBL8135240 | 0.78 | CA2 (0.60) | IDO1TAAR1CTBP2TDP1ALDH1A1 | |
| SCHEMBL6892256 | 0.77 | TAAR1 (0.52) | PLA2G1BATG4BLOXL2IDO1TAAR1 | |
| SCHEMBL10368085 | 0.76 | PLA2G1B (0.48) | PLA2G1BATG4BLOXL2IDO1TAAR1 | |
| SCHEMBL20269203 | 0.76 | SMN1; SMN2 (0.61) | IDO1TAAR1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1999167 | 0.76 | IDO1 (0.52) | IDO1TAAR1GAAAGXTCTBP2 | |
| SCHEMBL14109100 | 0.76 | IDO1 (0.43) | IDO1TAAR1MAPK8 | |
| SCHEMBL183375 | 0.76 | IDO1 (0.57) | LOXL2IDO1TAAR1GAAAGXT | |
| SCHEMBL13069072 | 0.76 | LOXL2 (0.48) | LOXL2IDO1TAAR1GAAAGXT | |
| SCHEMBL4879318 | 0.76 | IDO1 (0.47) | IDO1TAAR1AGXTCTBP2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-120040373-A | Thiazole GPR52 modulator compound | 江苏海洋大学 | 2025-05-27 | — | — | CN | disclosed |
| WO-2016202935-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |
| CN-103140136-B | fungicidal pyrazoles and mixtures thereof | DUPONT (US) | 2016-05-11 | — | — | CN | disclosed |