Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896762 | 0.91 | MAPT (0.44) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6902446 | 0.89 | NPY2R (0.47) | MAPTGAAMAPK1ALDH1A1KMT2A | |
| SCHEMBL6895056 | 0.89 | MAPT (0.43) | MAPTGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6052177 | 0.89 | MAPT (0.45) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7050368 | 0.88 | MAPT (0.42) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6897156 | 0.81 | MAPT (0.46) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7060964 | 0.80 | ALDH1A1 (0.44) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6901821 | 0.79 | MCHR1 (0.44) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6901950 | 0.79 | MCHR1 (0.44) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7050099 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |