SCHEMBL6895733

SCHEMBL6895733

Nc1cc(CP(=O)(O)O)ccc1CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 5/20 0.40
PGK2 P07205 5/20 0.40
ACP3 P15309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501606 0.84 PGK1 (0.43) PGK1PGK2ACP3
SCHEMBL16413297 0.83 GAA (0.52)
SCHEMBL16396701 0.78 ALDH1A1 (0.41)
SCHEMBL2676382 0.75 CA2 (0.56) PGK1PGK2
SCHEMBL987449 0.73 HPGD (0.45)
SCHEMBL29393814 0.73 HPGD (0.45)
SCHEMBL27351413 0.73 PGK1 (0.56) PGK1PGK2ACP3
SCHEMBL10931514 0.72 CAMK2A (0.51)
SCHEMBL10790173 0.72 HPGD (0.44)
SCHEMBL10790156 0.72 HPGD (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004039371-A2 COMPOSITIONS OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND NMDA RECEPTOR ANTAGONISTS FOR THE TREATMENT OR PREVENTION OF NEUROPATHIC PAIN PHARMACIA CORPORATION (US) 2004-05-13 WO claimed