Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502321 | 0.92 | MMP2 (0.47) | MMP2G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL1673477 | 0.86 | ALDH1A1 (0.46) | MMP2ALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL1355391 | 0.86 | ALDH1A1 (0.52) | MMP2G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL5135888 | 0.85 | MMP2 (0.52) | MMP2G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL3806401 | 0.85 | ALDH1A1 (0.44) | MMP2ALDH1A1HSD17B10KDM4ECDC25B | |
| SCHEMBL3622851 | 0.85 | PARP1 (0.46) | MMP2ALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28057982 | 0.83 | PARP1 (0.45) | MMP2ALDH1A1HSD17B10KDM4ECDC25B | |
| SCHEMBL282356 | 0.83 | ALDH1A1 (0.43) | MMP2ALDH1A1HSD17B10KDM4ECDC25B | |
| SCHEMBL8743511 | 0.82 | GABRP (0.49) | MMP2CASP6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL8479420 | 0.82 | MMP2 (0.57) | MMP2G6PDCASP7CASP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018188785-A1 | COMPOUND, COMPOUND FOR USE IN THE TREATMENT OF A PATHOLOGICAL CONDITION, A PHARMACEUTICAL COMPOSITION AND A METHOD FOR PREPARING SAID COMPOUND | Technische Universität München (DE) | 2018-10-18 | — | — | WO | claimed |
| EP-3388430-A1 | COMPOUND, COMPOUND FOR USE IN THE TREATMENT OF A PATHOLOGICAL CONDITION, A PHARMACEUTICAL COMPOSITION AND A METHOD FOR PREPARING SAID COMPOUND | Technische Universität München (DE) | 2018-10-17 | — | — | EP | claimed |
| EP-3229801-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-10-18 | — | — | EP | claimed |
| WO-2016094260-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-16 | — | — | WO | claimed |
| JP-2005533066-A | — | — | 2005-11-04 | — | — | JP | claimed |
| EP-1527070-A1 | AZOLE METHYLIDENE CYANIDE DERIVATIVES AND THEIR USE AS PROTEIN KINASE MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2005-05-04 | — | — | EP | claimed |
| WO-2005030709-A1 | NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE | LG LIFE SCIENCES LTD. (KR) | 2005-04-07 | — | — | WO | claimed |
| WO-2003106455-A1 | AZOLE METHYLIDENE CYANIDE DERIVATIVES AND THEIR USE AS PROTEIN KINASE MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-12-24 | — | — | WO | claimed |
| EP-0254009-B1 | A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1991-04-17 | — | — | EP | claimed |
| CN-119053211-A | Preparation method and application of ultra-small grain full-coverage infrared perovskite film | 河南省科学院物理研究所 | 2024-11-29 | — | — | CN | disclosed |
| US-12054491-B2 | Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators | UWM RESEARCH FOUNDATION, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-20240226165-A1 | Methods of Producing Improved Immune Cell Populations | Prescient Therapeutics Ltd (AU) | 2024-07-11 | — | — | US | disclosed |
| WO-2024013308-A2 | METHOD OF REDUCING NITRO COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2024-01-18 | — | — | WO | disclosed |
| EP-3450506-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, PRODUCTION METHOD THEREFOR, AND ELASTOMER MOLDED BODY | JXTG NIPPON OIL & ENERGY CORP (JP) | 2023-10-18 | — | — | EP | disclosed |
| US-5530028-A | CONTROLS INSECTS OF THE ORDER LEPIDOPTERA | ROHM AND HAAS COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5162336-A | Disorders of gastrointestinal, central nervous and appetite regulatory systems | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054491-B2 | Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators | GABRA5, GABRA4, GABRA1 | MMP2 3881/4885G6PD 4270/4885CASP7 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.