Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111374 | 0.88 | HTT (0.52) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL5219600 | 0.87 | ANPEP (0.46) | MEN1KMT2ADNM1ALDH1A1ANPEP | |
| SCHEMBL7054663 | 0.87 | DNM1 (0.55) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL27593038 | 0.87 | DNM1 (0.55) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL7118780 | 0.85 | BCHE (0.61) | MEN1KMT2AATMBCHEMAPK1 | |
| SCHEMBL7051763 | 0.84 | BCHE (0.59) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL7051118 | 0.83 | OPRD1 (0.47) | MEN1KMT2ADNM1ALDH1A1ANPEP | |
| SCHEMBL7112618 | 0.81 | DNM1 (0.49) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL27576822 | 0.81 | DNM1 (0.49) | MEN1KMT2ADNM1ALDH1A1HTT | |
| SCHEMBL7055848 | 0.81 | DNM1 (0.49) | MEN1KMT2ADNM1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |