Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219600 | 0.92 | ANPEP (0.46) | ALDH1A1CYP1A2CYP2D6LMNAMEN1 | |
| SCHEMBL7118780 | 0.85 | BCHE (0.61) | MEN1KMT2ABCHE | |
| SCHEMBL28748406 | 0.84 | MEN1 (0.39) | OPRD1OPRK1ALDH1A1SLC16A3LMNA | |
| SCHEMBL6895986 | 0.83 | MEN1 (0.51) | ALDH1A1MEN1KMT2ABCHEANPEP | |
| SCHEMBL28751162 | 0.81 | MEN1 (0.54) | ALDH1A1CYP1A2LMNAMEN1KMT2A | |
| SCHEMBL7112618 | 0.81 | DNM1 (0.49) | OPRD1OPRK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7054852 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL4427375 | 0.76 | DRD4 (0.59) | ALDH1A1DRD4MEN1KMT2ABCHE | |
| SCHEMBL7053301 | 0.75 | LMNA (0.47) | ALDH1A1CYP1A2CYP2D6LMNAMEN1 | |
| SCHEMBL7054663 | 0.75 | DNM1 (0.55) | ALDH1A1MEN1KMT2ABCHEDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |