Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624329 | 1.00 | SLC7A5 (0.54) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL14859907 | 0.89 | SLC7A5 (0.46) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| Hydroxyamine SCHEMBL20817080 | 0.83 | SLC7A5 (0.59) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL1200181 | 0.83 | RNPEP (0.57) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL28071461 | 0.82 | SLC7A5 (0.41) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6896640 | 0.80 | SLC7A5 (0.50) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL28745057 | 0.80 | SLC7A5 (0.67) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25381978 | 0.77 | MMP8 (0.50) | — | |
| SCHEMBL6826049 | 0.77 | MMP3 (0.46) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6896224 | 0.77 | MME (0.50) | SLC7A5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | claimed |
| US-10428012-B2 | Method of preparation of 4-isopropylamino-1-butanol | SEASONS BIOTECHNOLOGY CO., LTD. (CN) | 2019-10-01 | — | — | US | disclosed |
| US-20190084921-A1 | METHOD OF PREPARATION OF 4-ISOPROPYLAMINO-1-BUTANOL | SEASONS BIOTECHNOLOGY TAIZHOU CO LTD (CN) | 2019-03-21 | — | — | US | disclosed |
| US-10144701-B2 | Method for preparing 4-isopropylamino-1-butanol | Seasons Biotechnology (Taizhou) Co., Ltd. (CN) | 2018-12-04 | — | — | US | disclosed |
| US-20180029973-A1 | METHOD FOR PREPARING 4-ISOPROPYLAMINO-1-BUTANOL | Seasons Biotechnology (Taizhou) Co., Ltd. (CN) | 2018-02-01 | — | — | US | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1189638-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2001000187-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0444482-A2 | Oxetanones | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084921-A1 | METHOD OF PREPARATION OF 4-ISOPROPYLAMINO-1-BUTANOL | ADH1A, ADH1C, ADH5 | SLC7A5 3661/4885RNPEP 1632/4885SLC1A3 4347/4885 |
| US-10428012-B2 | Method of preparation of 4-isopropylamino-1-butanol | ADH1A, ADH1C, ADH5 | SLC7A5 3661/4885RNPEP 1632/4885SLC1A3 4347/4885 |
| US-20180029973-A1 | METHOD FOR PREPARING 4-ISOPROPYLAMINO-1-BUTANOL | ADH1A, ADH1C, ADH5 | SLC7A5 3420/4885RNPEP 1660/4885SLC1A3 4168/4885 |
| US-10144701-B2 | Method for preparing 4-isopropylamino-1-butanol | ADH1A, ADH1C, ADH5 | SLC7A5 3420/4885RNPEP 1660/4885SLC1A3 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.