Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897228 | 1.00 | SLC7A5 (0.54) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL14859907 | 0.89 | SLC7A5 (0.46) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| Hydroxyamine SCHEMBL20817080 | 0.83 | SLC7A5 (0.59) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL1200181 | 0.83 | RNPEP (0.57) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL28071461 | 0.82 | SLC7A5 (0.41) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6896640 | 0.80 | SLC7A5 (0.50) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL28745057 | 0.80 | SLC7A5 (0.67) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25381978 | 0.77 | MMP8 (0.50) | — | |
| SCHEMBL6826049 | 0.77 | MMP3 (0.46) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6896224 | 0.77 | MME (0.50) | SLC7A5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | claimed |
| CN-117783357-A | Method for detecting potential genotoxic impurity 2-halogenated alkyl acid in drug starting material by GC-MS | 上海博悦生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115105476-B | Orlistat freeze-dried oral preparation and preparation process thereof | 山东新时代药业有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-114555061-B | Oligostat capsule and preparation method thereof | 山东新时代药业有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-115105476-A | Orlistat freeze-dried oral preparation and preparation process thereof | 山东新时代药业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| EP-1189638-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000187-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |