Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983304 | 0.86 | LMNA (0.54) | ALDH1A1CYP1A2TP53SMN1; SMN2KDM4E | |
| SCHEMBL6897135 | 0.84 | LMNA (0.45) | ALDH1A1TDP1CYP1A2TP53SMN1; SMN2 | |
| SCHEMBL499116 | 0.82 | GAA (0.61) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL6822746 | 0.81 | MAPK1 (0.56) | ALDH1A1GAACYP2C19CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4002124 | 0.81 | GAA (0.59) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL27961458 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TP53SMN1; SMN2KDM4E | |
| SCHEMBL29141728 | 0.74 | PTPN1 (0.52) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL9828028 | 0.74 | MEN1 (0.62) | ALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL7823257 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL6926630 | 0.74 | MEN1 (0.64) | ALDH1A1GAATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |