Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18272456 | 0.75 | ALDH1A1 (0.67) | ALDH1A1HSD17B10LMNACYP2C19TP53 | |
| SCHEMBL15168483 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HTTKMT2ALMNA | |
| SCHEMBL22205141 | 0.71 | HTT (0.49) | ALDH1A1HSD17B10HTTKMT2ALMNA | |
| SCHEMBL9537754 | 0.70 | ALDH1A1 (0.79) | ALDH1A1HTTKMT2ALMNACYP2C19 | |
| SCHEMBL10971944 | 0.69 | ALDH1A1 (0.69) | ALDH1A1HTTKMT2ALMNACYP2C19 | |
| SCHEMBL31272882 | 0.69 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HTTKMT2ALMNA | |
| SCHEMBL31619712 | 0.68 | ALDH1A1 (0.73) | ALDH1A1HSD17B10KMT2ALMNACYP2C19 | |
| SCHEMBL21916114 | 0.66 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HTTKMT2ALMNA | |
| SCHEMBL9053738 | 0.65 | ALDH1A1 (0.64) | ALDH1A1HSD17B10LMNACYP2C19RAB9A | |
| SCHEMBL19061351 | 0.64 | ALDH1A1 (0.49) | ALDH1A1HSD17B10HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160271137-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | UNIV PRINCETON (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160271137-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | UNIV PRINCETON (US) | 2016-09-22 | — | — | US | disclosed |
| US-9168269-B2 | Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-27 | — | — | US | disclosed |
| US-9168269-B2 | Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150139949-A1 | ANTI-VIRAL COMBINATION THERAPY | KOYUNCU EMRE (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150139949-A1 | ANTI-VIRAL COMBINATION THERAPY | KOYUNCU EMRE (US) | 2015-05-21 | — | — | US | disclosed |
| US-20130190381-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190381-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2012139028-A2 | ANTI-VIRAL COMBINATION THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
| WO-2011103516-A2 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271137-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | FASN, PLIN1, PLIN3 | ALDH1A1 3031/4885HSD17B10 63/4885HTT 3585/4885 |
| US-20130190381-A1 | INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS | FASN, PLIN1, PLIN3 | ALDH1A1 3031/4885HSD17B10 63/4885HTT 3585/4885 |
| US-20150139949-A1 | ANTI-VIRAL COMBINATION THERAPY | HAVCR2, MAVS, ZC3HAV1 | ALDH1A1 1175/4885HSD17B10 875/4885HTT 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.