SCHEMBL68975

SCHEMBL68975

Cc1c(Cc2ccc(O)c(C(C)C)c2C)ccc(O)c1C(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.37
TYR P14679 4/20 0.34
ALOX12 P18054 4/20 0.33
USP2 O75604 3/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 3/20 0.33
ALOX15 P16050 3/20 0.33
HIF1A Q16665 3/20 0.33
HSPA5 P11021 2/20 0.33
ESR1 P03372 2/20 0.33
MEN1 O00255 2/20 0.33
CYP3A4 P08684 2/20 0.33
HTT P42858 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ESR2 Q92731 1/20 0.33
SLC22A1 O15245 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282461 0.87 ESR1 (0.39) AMY1ATYRESR1ESR2GPR55
SCHEMBL21195120 0.80 TRPA1 (0.39) TYRALOX12USP2LMNAHPGD
SCHEMBL1970931 0.76 TRPA1 (0.45) TYRALOX12LMNAHIF1AESR1
SCHEMBL4063406 0.75 TYR (0.44) AMY1ATYRALOX12USP2LMNA
SCHEMBL283236 0.75 THRA (0.53) GAA
SCHEMBL31438162 0.74 LMNA (0.48) TYRALOX12LMNAHPGDHIF1A
SCHEMBL1487374 0.74 LMNA (0.48) TYRALOX12LMNAHPGDHIF1A
SCHEMBL1760433 0.74 TYR (0.44) TYRALOX12USP2LMNAHPGD
SCHEMBL30360391 0.74 TYR (0.44) TYRALOX12USP2LMNAHPGD
SCHEMBL23841449 0.73 TYR (0.41) TYRALOX12ALOX15ESR1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 AMY1A 2199/4885TYR 134/4885ALOX12 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.