SCHEMBL4063406

SCHEMBL4063406

Cc1c(O)ccc(Cc2ccc(O)c(C)c2C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.44
AMY1A P0DUB6 1/20 0.43
HSPA5 P11021 2/20 0.40
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HIF1A Q16665 2/20 0.39
MEN1 O00255 1/20 0.39
SLC22A1 O15245 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HSPD1 P10809 1/20 0.39
IDO1 P14902 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28648896 0.84 ALOX5 (0.42) TYRAMY1AHSPA5ESR1ESR2
SCHEMBL6687761 0.83 BCL2 (0.55) SMN1; SMN2HIF1AMEN1CYP3A4MAPT
SCHEMBL4888228 0.82 TYR (0.47) TYRESR1ESR2HSP90AA1TRPA1
SCHEMBL31244461 0.82 TYR (0.57) TYRAMY1AHSPA5ESR1ESR2
SCHEMBL8470006 0.82 TYR (0.57) TYRAMY1AHSPA5ESR1ESR2
SCHEMBL23919938 0.82 AMY1A (0.47) TYRAMY1AHSPA5ESR1ESR2
SCHEMBL3468895 0.82 TYR (0.42) TYRAMY1AESR1ESR2SMN1; SMN2
SCHEMBL30597484 0.82 TYR (0.47) TYRESR1ESR2HSP90AA1TRPA1
SCHEMBL11154126 0.80 TYR (0.41) TYRAMY1AESR1ESR2MEN1
SCHEMBL29457565 0.80 TRPA1 (0.53) TYRESR1ESR2HIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207788-B1 FROM 2,6-DIMETHYLOL-4-METHYLPHENOL AND BIS(2,5-DIMETHYL-4-HYDROXYPHENYL)METHANE TOKYO OHKA KOGYA CO., LTD. (JP) 2001-03-27 US claimed
US-20210294214-A1 UNDERLAYER FILM FORMING COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-09-23 US disclosed
EP-3832390-A1 UNDERLAYER FILM-FORMING COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-06-09 EP disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-0385778-B1 Fuel oil compositions EXXON CHEMICAL PATENTS INC (US) 1996-12-11 EP disclosed
EP-0391735-B1 Fuel oil compositions EXXON CHEMICAL PATENTS INC (US) 1995-08-16 EP disclosed
US-5348561-A Quaternary ammonium stabilizers to prevent sedimentation and color formation during storage EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US disclosed
EP-0388236-B1 Fuel oil compositions EXXON CHEMICAL PATENTS INC (US) 1993-11-24 EP disclosed
US-5152807-A Discoloration inhibition EXXON CHEMICAL PATENTS INC. (US) 1992-10-06 US disclosed
US-5034496-A High impact strength and tough polycarbonates THE DOW CHEMICAL COMPANY (US) 1991-07-23 US disclosed
EP-0391735-A1 Fuel oil compositions EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0388236-A1 Fuel oil compositions EXXON CHEMICAL PATENTS INC. (US) 1990-09-19 EP disclosed
EP-0286877-A2 Polycarbonate compositions and process for preparing the same THE DOW CHEMICAL COMPANY (US) 1988-10-19 EP disclosed
US-4204047-A AN AROMTIC POLYCARBONATE, POLYMERS OF SYTRENE AND/OR METHYL METHACRYLATE AND AN ACRYLONITRILE GRAFTED ON RUBBER AND WITH AN N-SUBSTITUTED MALEIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM TYR 1522/4885AMY1A 2387/4885HSPA5 4266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.