Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 14/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777932 | 0.87 | MAPT (0.43) | CCR3HTR2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6777509 | 0.87 | FAAH (0.47) | MEN1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL6769799 | 0.86 | MCHR1 (0.50) | — | |
| SCHEMBL14592805 | 0.86 | CCR3 (0.49) | CCR3HTR2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL6779213 | 0.86 | KMT2A (0.49) | CCR3HTR2ANPC1RAB9AMAPT | |
| SCHEMBL6783081 | 0.86 | MAPT (0.42) | CCR3SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL6776742 | 0.83 | CCR3 (0.48) | CCR3HTR2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6777400 | 0.81 | CCR3 (0.45) | CCR3HTR2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6778468 | 0.80 | HDAC3 (0.49) | CCR3SMN1; SMN2NPC1L3MBTL1MEN1 | |
| SCHEMBL6784710 | 0.80 | GLO1 (0.38) | L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402528-C | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | claimed |
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |