Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777509 | 0.89 | FAAH (0.47) | MAPTKDM4EKMT2AGAAHPGD | |
| SCHEMBL6779213 | 0.88 | KMT2A (0.49) | MAPTCCR3NPC1RAB9AKMT2A | |
| SCHEMBL6783081 | 0.88 | MAPT (0.42) | MAPTKDM4ECCR3SMN1; SMN2NPC1 | |
| SCHEMBL6897844 | 0.87 | CCR3 (0.46) | MAPTCCR3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6783335 | 0.82 | CCR3 (0.46) | MAPTKDM4ECCR3SMN1; SMN2NPC1 | |
| SCHEMBL6778468 | 0.82 | HDAC3 (0.49) | MAPTCCR3SMN1; SMN2NPC1KMT2A | |
| SCHEMBL6768483 | 0.81 | DRD3 (0.44) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6098139 | 0.81 | DYRK1A (0.37) | KDM4ERXFP1 | |
| SCHEMBL6773196 | 0.80 | ALDH1A1 (0.39) | KMT2A | |
| SCHEMBL6773506 | 0.80 | NPC1 (0.47) | MAPTKDM4ECCR3TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402528-C | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | claimed |
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |