Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772103 | 0.87 | MCHR1 (0.51) | MCHR1NAMPTGAADRD3 | |
| SCHEMBL6897844 | 0.86 | CCR3 (0.46) | — | |
| SCHEMBL6768483 | 0.86 | DRD3 (0.44) | HDAC3GAADRD3 | |
| SCHEMBL3867357 | 0.85 | MCHR1 (0.49) | MCHR1NAMPTHDAC3ADORA2AGAA | |
| SCHEMBL6773542 | 0.84 | TP53BP1 (0.48) | NAMPTHDAC3GPR139DRD3 | |
| SCHEMBL6773548 | 0.84 | HDAC3 (0.49) | HDAC3DRD3 | |
| SCHEMBL6773077 | 0.82 | MCHR1 (0.49) | MCHR1NAMPTHDAC3ADORA2AGAA | |
| SCHEMBL6784710 | 0.81 | GLO1 (0.38) | — | |
| SCHEMBL6774052 | 0.81 | POLB (0.43) | NAMPTHDAC3GAADRD3 | |
| SCHEMBL6773218 | 0.80 | MCHR1 (0.47) | MCHR1NAMPTHDAC3ADORA2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |