Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449283 | 0.76 | CCR5 (0.51) | SMN1; SMN2CCR5LMNAHTTRAB9A | |
| SCHEMBL14511752 | 0.76 | SLC6A4 (0.52) | SMN1; SMN2CCR5LMNAHTTRAB9A | |
| SCHEMBL6784368 | 0.75 | — | — | |
| SCHEMBL7073094 | 0.75 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4875917 | 0.74 | GLRA1 (0.50) | THRATHRBSMN1; SMN2KDM4EELANE | |
| SCHEMBL4874863 | 0.73 | MEN1 (0.48) | SMN1; SMN2MEN1KMT2AELANE | |
| SCHEMBL14511787 | 0.73 | PTGER1 (0.45) | SMN1; SMN2KDM4ECCR5MAPTMAPK1 | |
| SCHEMBL1107091 | 0.73 | PTGER1 (0.45) | SMN1; SMN2CCR5MAPTMAPK1TDP1 | |
| SCHEMBL2901054 | 0.72 | MAOB (0.47) | SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL30008548 | 0.72 | MEN1 (0.44) | MEN1KMT2AKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980951-B2 | Sesquiterpenes for antifungal applications | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140135404-A1 | SESQUITERPENES FOR ANTIFUNGAL APPLICATIONS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-05-15 | — | — | US | disclosed |
| US-6727277-B1 | BENZO(A)XANTHENE DERIVATIVES; LYMPHATIC ABSORPTION INTENSIFIERS 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE INHIBITORS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2004-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135404-A1 | SESQUITERPENES FOR ANTIFUNGAL APPLICATIONS | DPM1, ERG28, MDN1 | THRA 3948/4885THRB 4014/4885MAPK14 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.