Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18789242 | 0.87 | ALDH1A1 (0.55) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL763137 | 0.80 | CACNA2D1 (0.43) | LOXL2CYP3A4TDP1TSHRMEN1 | |
| SCHEMBL8526226 | 0.78 | LOXL2 (0.50) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL8381197 | 0.78 | ALDH1A1 (0.46) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL19934042 | 0.78 | TSHR (0.46) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL6563096 | 0.77 | EPHX1 (0.56) | LOXL2MAOASLC6A4 | |
| SCHEMBL1912772 | 0.76 | LOXL2 (0.48) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL19934200 | 0.75 | TDP1 (0.42) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL1048212 | 0.74 | ALDH1A1 (0.52) | LOXL2ALDH1A1CYP3A4TDP1GFER | |
| SCHEMBL6449520 | 0.73 | SLC6A4 (0.60) | MAOBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-12-31 | — | — | US | disclosed |
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-02-27 | — | — | US | disclosed |
| WO-2019173639-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| WO-2018045385-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| EP-0699079-B1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES COMPRISING GENETIC MATERIALS | DOW CHEMICAL CO (US) | 2004-09-29 | — | — | EP | disclosed |
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0271180-B2 | Starburst conjugates | DOW CHEMICAL CO (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5527524-A | AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0699079-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1995024221-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5338532-A | Star polymer as carrier for drugs, agricultural compounds | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0271180-A1 | Starburst conjugates | THE DOW CHEMICAL COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988001178-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001179-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001180-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | LOXL2 4139/4885ALDH1A1 2862/4885CYP3A4 4194/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | LOXL2 4139/4885ALDH1A1 2862/4885CYP3A4 4194/4885 |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | LOXL2 4139/4885ALDH1A1 2862/4885CYP3A4 4194/4885 |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | LOXL2 4139/4885ALDH1A1 2862/4885CYP3A4 4194/4885 |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | LOXL2 4139/4885ALDH1A1 2862/4885CYP3A4 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.