Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.42 |
| ▸ | CHRNG | P07510 | 3/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.42 |
| ▸ | CHRND | Q07001 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895814 | 0.95 | CTSS (0.42) | MMP8KIFC1SRC | |
| SCHEMBL6899419 | 0.94 | KIFC1 (0.45) | MMP8MMP2MMP9KIFC1SRC | |
| SCHEMBL27538457 | 0.92 | AVPR1A (0.46) | MMP8CTSLKIFC1SRC | |
| SCHEMBL6899191 | 0.92 | AVPR1A (0.46) | MMP8CTSLKIFC1SRC | |
| SCHEMBL6890698 | 0.92 | KIFC1 (0.42) | MMP8CTSLKIFC1SRC | |
| SCHEMBL6897068 | 0.91 | KMT2A (0.47) | OPRM1OPRD1MMP2MMP9CTSL | |
| SCHEMBL6895729 | 0.91 | MEN1 (0.41) | MMP8CTSLKIFC1SRC | |
| SCHEMBL6890575 | 0.89 | SRC (0.42) | OPRM1OPRD1MMP8KIFC1SRC | |
| SCHEMBL6890418 | 0.89 | ALDH1A1 (0.44) | CTSL | |
| SCHEMBL6897220 | 0.89 | MME (0.44) | MMP8MMP2MMP9CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | OPRM1 41/4885OPRD1 43/4885OPRK1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.