SCHEMBL5166735

SCHEMBL5166735

Cc1ccc(C(=O)NNC(=O)c2ccccc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.83
GAA P10253 1/20 0.83
CCR6 P51684 1/20 0.74
PTGS2 P35354 1/20 0.72
POLB P06746 4/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
LMNA P02545 1/20 0.69
RAB9A P51151 6/20 0.67
NPC1 O15118 5/20 0.67
CTDSP1 Q9GZU7 2/20 0.67
MAPT P10636 2/20 0.66
CES2 O00748 1/20 0.65
CES1 P23141 1/20 0.65
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
HTT P42858 1/20 0.62
KDM4E B2RXH2 2/20 0.62
TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103221 0.91 ALDH1A1 (1.00) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL14527271 0.90 CTDSP1 (0.78) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL12324391 0.89 RAB9A (0.82) ALDH1A1GAAPTGS2POLBSMN1; SMN2
SCHEMBL6463624 0.87 LMNA (0.69) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL22429059 0.86 CCR6 (1.00) ALDH1A1GAACCR6POLBSMN1; SMN2
SCHEMBL400890 0.86 RAB9A (0.77) ALDH1A1GAAPTGS2POLBSMN1; SMN2
SCHEMBL11888632 0.85 ALDH1A1 (0.73) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL11783307 0.84 PTGS2 (0.86) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL6898441 0.84 PTGS2 (1.00) ALDH1A1GAACCR6PTGS2POLB
SCHEMBL3724445 0.84 RAB9A (0.68) ALDH1A1GAACCR6PTGS2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1030911-C Dibenzoylalkylcyanohydrazines ROHM & HAAS (US) 1996-02-07 CN claimed
CN-1057452-A Dibenzoyl alkyl-alkyl cyanides ROHM & HAAS (US) 1992-01-01 CN claimed
EP-2862883-B1 METHOD FOR PRODUCING NUCLEATOR MASTERBATCH ADEKA CORP (JP) 2019-09-25 EP disclosed
US-9243127-B2 Method for producing nucleator masterbatch ADEKA CORPORATION (JP) 2016-01-26 US disclosed
US-20150152248-A1 METHOD FOR PRODUCING NUCLEATOR MASTERBATCH ADEKA CORPORATION (JP) 2015-06-04 US disclosed
EP-2862883-A1 METHOD FOR PRODUCING NUCLEATOR MASTERBATCH Adeka Corporation (JP) 2015-04-22 EP disclosed
EP-2319882-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2013-10-09 EP disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
EP-2319882-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-05-11 EP disclosed
EP-1774629-A1 VERTICAL CAVITY LASER PRODUCING DIFFERENT COLOR LIGHT EASTMAN KODAK COMPANY (US) 2007-04-18 EP disclosed
EP-1754103-A1 DIRECT-VIEW DISPLAY DEVICES USING VERTICAL CAVITY LASER ARRAYS EASTMAN KODAK COMPANY (US) 2007-02-21 EP disclosed
EP-1683212-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY (US) 2006-07-26 EP disclosed
WO-2005124442-A1 DIRECT-VIEW DISPLAY DEVICES USING VERTICAL CAVITY LASER ARRAYS EASTMAN KODAK COMPANY (US) 2005-12-29 WO disclosed
WO-2005119865-A1 VERTICAL CAVITY LASER PRODUCING DIFFERENT COLOR LIGHT EASTMAN KODAK COMPANY (US) 2005-12-15 WO disclosed
WO-2005061521-A1 SYNTHESIS OF BIS(AZINYL)AMINE-BF2 COMPLEX EASTMAN KODAK COMPANY (US) 2005-07-07 WO disclosed
WO-2005048370-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY (US) 2005-05-26 WO disclosed
WO-2004109398-A1 PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED COUPLER MOIETY EASTMAN KODAK COMPANY (US) 2004-12-16 WO disclosed