Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899688 | 1.00 | IDO1 (0.42) | IDO1KEAP1NFE2L2KDM4ELMNA | |
| SCHEMBL6898544 | 1.00 | IDO1 (0.42) | IDO1KEAP1NFE2L2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6898738 | 0.98 | IDO1 (0.44) | IDO1KEAP1NFE2L2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6898731 | 0.98 | IDO1 (0.44) | IDO1KEAP1NFE2L2KDM4ELMNA | |
| SCHEMBL6896239 | 0.81 | GABBR2 (0.45) | KDM4ELMNAMAPK1KIF11METAP2 | |
| SCHEMBL6896230 | 0.81 | GABBR2 (0.45) | KDM4ELMNAMAPK1KIF11METAP2 | |
| SCHEMBL6897515 | 0.79 | SLC6A2 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL6896284 | 0.79 | SLC6A2 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL6898442 | 0.76 | METAP2 (0.44) | KDM4EKIF11METAP2METAP1DPP8 | |
| SCHEMBL6898450 | 0.76 | METAP2 (0.44) | KDM4EKIF11METAP2METAP1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317461-B1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1317461-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6509472-B2 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2003-01-21 | — | — | US | disclosed |
| US-20020038053-A1 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2002-03-28 | — | — | US | disclosed |
| WO-2002022623-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038053-A1 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | ADH5, ADH1A, ADH1C | IDO1 2531/4885KEAP1 2794/4885NFE2L2 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.