Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903898 | 0.85 | CYP3A4 (0.37) | CCR1CCR5CCR8HDAC6TP53 | |
| SCHEMBL6902359 | 0.84 | CYP3A4 (0.36) | KDM4EALDH1A1HPGDTDP1CCR1 | |
| SCHEMBL6902522 | 0.83 | CCR1 (0.37) | CCR1CCR5CCR8HDAC6TP53 | |
| SCHEMBL6901048 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1CCR1 | |
| Hydrochloric Acid SCHEMBL6905141 | 0.83 | CYP11B1 (0.36) | KDM4EALDH1A1HPGDCYP11B1CYP11B2 | |
| SCHEMBL7592887 | 0.79 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDTDP1MAOA | |
| SCHEMBL6897160 | 0.79 | CCR1 (0.33) | CCR1CCR5CCR8HDAC6 | |
| SCHEMBL6901825 | 0.79 | ALDH1A1 (0.34) | ALDH1A1CCR1CCR5CCR8HDAC6 | |
| SCHEMBL6902565 | 0.78 | CCR1 (0.32) | CCR1CCR5CCR8HDAC6 | |
| SCHEMBL6902299 | 0.78 | CCR1 (0.32) | CCR1CCR5CCR8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |