SCHEMBL6902565

SCHEMBL6902565

Cc1ccc(C2=Cc3c(-c4ccc(C(C)C)cc4)cccc3C2[Zr]C2C(c3ccc(C)cn3)=Cc3c(-c4ccc(C(C)C)cc4)cccc32)nc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.32
CCR5 P51681 1/20 0.32
CCR8 P51685 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2A6 P11509 1/20 0.31
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902522 0.91 CCR1 (0.37) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6902617 0.90 ALOX5AP (0.30)
SCHEMBL6903898 0.88 CYP3A4 (0.37) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6901825 0.86 ALDH1A1 (0.34) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6897160 0.86 CCR1 (0.33) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6902299 0.85 CCR1 (0.32) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6902406 0.84 TGFBR1 (0.39)
SCHEMBL6902359 0.84 CYP3A4 (0.36) CCR1CCR5CCR8HDAC6CYP3A4
Hydrochloric Acid SCHEMBL7733570 0.84 CYP3A4 (0.33) CCR1CCR5CCR8HDAC6CYP3A4
SCHEMBL6902576 0.83 SMN1; SMN2 (0.33) CCR1CCR5CCR8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033371-B1 Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2004-01-28 EP claimed