Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503395 | 0.77 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6899805 | 0.74 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25976215 | 0.73 | NPC1 (0.38) | BACE1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL24359494 | 0.72 | EGFR (0.39) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30306713 | 0.71 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| Lithium SCHEMBL29601477 | 0.71 | EGFR (0.38) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13773460 | 0.71 | PDE4B (0.49) | BACE1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL8905382 | 0.71 | CA2 (0.39) | TSHRALDH1A1 | |
| SCHEMBL8028400 | 0.70 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6320031 | 0.70 | NPC1 (0.42) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828269-B2 | Chromium compound,aryloxy compound of a magnesium, calcium, strontium and barium; hydrocarbylaluminum and aluminoxane compounds | INSTITUT FRANCAIS DU PETROLE (FR) | 2004-12-07 | — | — | US | disclosed |
| US-20010023281-A1 | Catalytic composition and a process for oligomerizing ethylene, in particular to 1-hexene | INSTITUT FRANCAIS DU PETROLE (FR) | 2001-09-20 | — | — | US | disclosed |