Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157367 | 0.79 | PDF (0.38) | — | |
| SCHEMBL19210480 | 0.72 | CYP2D6 (0.48) | ALDH1A1 | |
| SCHEMBL19872813 | 0.70 | HPGD (0.45) | HPGDALDH1A1 | |
| SCHEMBL3157408 | 0.70 | TGFBR1 (0.32) | — | |
| SCHEMBL3156097 | 0.70 | TGFBR1 (0.32) | — | |
| SCHEMBL224143 | 0.69 | ALDH1A1 (0.37) | HPGDALDH1A1 | |
| SCHEMBL5251240 | 0.68 | ECE1 (0.33) | — | |
| SCHEMBL9280801 | 0.68 | HPGD (0.31) | HPGDALDH1A1 | |
| SCHEMBL23855055 | 0.68 | TGFBR1 (0.36) | ALDH1A1 | |
| SCHEMBL394954 | 0.68 | TGFBR1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414802-A1 | HETEROARYLHETEROALKYLAMINE DERIVATIVES AND THEIR USE AS INHIBITORS OF NITRIC OXIDE SYNTHASE | AstraZeneca AB (SE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011830-A1 | HETEROARYLHETEROALKYLAMINE DERIVATIVES AND THEIR USE AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2003-02-13 | — | — | WO | disclosed |