Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156097 | 1.00 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL224143 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL23855055 | 0.72 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL394954 | 0.72 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL1069360 | 0.72 | OR51E2 (0.33) | TGFBR1 | |
| SCHEMBL4595646 | 0.72 | MME (0.34) | TGFBR1 | |
| SCHEMBL31577906 | 0.70 | MEN1 (0.37) | — | |
| SCHEMBL6900065 | 0.70 | HPGD (0.33) | — | |
| SCHEMBL3910231 | 0.69 | LAP3 (0.41) | — | |
| SCHEMBL21747185 | 0.69 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150269-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008139986-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC., (JP) | 2008-11-20 | — | — | WO | disclosed |