Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SELL | P14151 | 3/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FUT4 | P22083 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943673 | 0.78 | HSD17B10 (0.44) | LMNAALDH1A1MAPTHSD17B10CA2 | |
| SCHEMBL3217327 | 0.78 | CA1 (0.56) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL8396691 | 0.78 | TTR (0.44) | LMNATDP1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6899643 | 0.78 | SERPINE1 (0.38) | KDM4ELMNATDP1SELLSELP | |
| SCHEMBL6474809 | 0.73 | ALDH1A1 (0.53) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL11698902 | 0.73 | TSHR (0.42) | KDM4ELMNATDP1SELLSELP | |
| SCHEMBL11046141 | 0.72 | KDM4E (0.42) | KDM4ELMNATDP1SELLSELP | |
| SCHEMBL11408792 | 0.71 | CA1 (0.52) | KDM4ELMNATDP1SELLSELP | |
| SCHEMBL1528872 | 0.70 | CYP19A1 (0.46) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL68262 | 0.69 | ACHE (0.55) | KDM4ELMNATDP1SELLSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967094-B | Phenylacetyl quinic acid of witlooves and ester compound thereof | LI GUOYU | 2013-06-19 | — | — | CN | claimed |
| CN-101967094-A | Phenylacetyl quinic acid of witlooves and ester compound thereof | GUOYU LI | 2011-02-09 | — | — | CN | claimed |
| EP-1171130-A4 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |
| US-20030078212-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. | 2003-04-24 | — | — | US | claimed |
| JP-2002540060-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1171130-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2002-01-16 | — | — | EP | claimed |
| WO-2000025787-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-101967094-B | Phenylacetyl quinic acid of witlooves and ester compound thereof | LI GUOYU | 2013-06-19 | — | — | CN | disclosed |
| CN-101967094-A | Phenylacetyl quinic acid of witlooves and ester compound thereof | GUOYU LI | 2011-02-09 | — | — | CN | disclosed |
| EP-1171130-A4 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARM INC (US) | 2004-05-19 | — | — | EP | disclosed |
| US-20030078212-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. | 2003-04-24 | — | — | US | disclosed |
| EP-1171130-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000025787-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-4560749-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| US-4521598-A | 3-Azidocephalosporins | ELI LILLY AND COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| EP-0136177-A2 | 3-Azidocephalosporins as intermediates and novel antibacterial agents | ELI LILLY AND COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078212-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | PARP10, PARG, DERA | KDM4E 1091/4885LMNA 99/4885TDP1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.