SCHEMBL6900210

SCHEMBL6900210

Cc1c(C)c2c(c(C)c1O)C(C)c1c(C)c(O)c(C)c(C)c1O2

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.44
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NUAK1 O60285 1/20 0.32
IGF1R P08069 1/20 0.32
MET P08581 1/20 0.32
SRC P12931 1/20 0.32
AXL P30530 1/20 0.32
KDR P35968 1/20 0.32
NEK2 P51955 1/20 0.32
PTK2 Q05397 1/20 0.32
AURKB Q96GD4 1/20 0.32
ALK Q9UM73 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904469 0.76 ALOX5 (0.36) ALOX5
SCHEMBL6905384 0.76 ALOX5 (0.44) ALOX5ESR1ESR2NUAK1IGF1R
SCHEMBL3278459 0.71 ALOX5 (0.51) ALOX5
SCHEMBL6906681 0.67 ALOX5 (0.41) ALOX5NUAK1IGF1RMETSRC
Durohydroquinone SCHEMBL69786 0.66 ALOX5 (0.38) ALOX5
SCHEMBL5588363 0.66 ALOX5 (0.33) ALOX5
SCHEMBL13592378 0.66 ALOX5 (0.39) ALOX5
SCHEMBL7867773 0.65 ALOX5 (0.42) ALOX5ESR1ESR2NUAK1IGF1R
SCHEMBL6906639 0.62 ACHE (0.36) ESR1ESR2
SCHEMBL397768 0.62 ALOX5 (0.36) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed