SCHEMBL6906639

SCHEMBL6906639

Cc1c(O)cc2c(c1C)Oc1c(cc(O)c(C)c1C)C2C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
ESR1 P03372 3/20 0.33
ESR2 Q92731 3/20 0.33
CYP3A4 P08684 1/20 0.31
CDK1 P06493 2/20 0.30
CCNB1 P14635 2/20 0.30
CCNE1 P24864 2/20 0.30
CDK2 P24941 2/20 0.30
CDK7 P50613 2/20 0.30
CCNH P51946 2/20 0.30
MNAT1 P51948 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904941 0.79 ESR1 (0.33) ACHEESR1ESR2CYP3A4
SCHEMBL28818061 0.69 MAOA (0.41) ACHE
SCHEMBL6903662 0.68 AKT1 (0.37) ACHECYP3A4
SCHEMBL28120205 0.67 KDM4E (0.38) ESR1CYP3A4
SCHEMBL17934025 0.64 UHRF1 (0.30)
SCHEMBL9908633 0.62 SELL (0.33) ACHE
SCHEMBL13868615 0.62 SELL (0.33) ACHE
SCHEMBL6900210 0.62 ALOX5 (0.44) ESR1ESR2
SCHEMBL68071 0.62 ACHE (0.59) ACHEESR1ESR2CYP3A4
SCHEMBL13868616 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed